99%+ Purity Tetracaine Base CAS 94-24-6

Product Details:

 

Tetracaine Powder Information
Tetracaine Price1kgAccording to your needs
25kgAccording to your needs
500kgAccording to your needs
Packaging25kg/drum
Delivery timeAbout 7 days
ShippingEMS, Hongkong Post, DHL, TNT, Fedex and so on.
Payment termsWU, MG, Bitcoin, T/T
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1kg powder

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Local Anesthetic Tetracaine Base CAS 94-24-6 For Pain Killer White Powder

 

Product name: 2- (Dimethylamino) ethyl 4- (n-butylamino) benzoate
Synonym: tetracaine usp; tetracaine free base; Tetracaine Base; amethocaine; Dimethylaminoethylnbutylaminobenzoate; Tetracaine; 2- (dimethylamino) ethyl 4- (butylamino) benzoate
CAS: 94-24-6
EINECS Number: 202-316-6
Formula: C15H24N2O2
MW: 264.3633
Density: 1.044g / cm3
Boiling point: 389.4 ° C at 760 mmHg
Flash Point: 189.3 ° C
Vapor Pressure: 2.87E-06mmHg at 25 ° C
Assay:99%
Appearance:White crystalline powder

 

Tetracaine Base Specifications:

COA

Assay(*)98~101.0%100.4%

Identification
A.By UV, To match with working standardComplies
 B: Dissolve 100 mg in 10 mL of water, and add 1 mL of potassium thiocyanate
solution (1 in 4): a crystalline precipitate is formed. Recrystallize the precipitate
from water, and dry at 80 for 2 hours: it melts between 130 and 132 .

Complies
 C. A solution of 100 mg in 5 mL of water meets the requirements of the
Tests for Chloride

Complies
PH
Chromatographic purity
Clarity
4.5~6.55.9
 Conform to standardComplies
 Solution should be clearComplies
Related SubstancesNot more than the reference solution (0.05%)Complies
Heavy metals≤10ppm<10ppm
Loss on drying<0.5%0.21%
Resiue on ignition≤0.1%0.05%
Melting range145~150°C146~149°C
Molecular formula

 

Tetracaine Base Description:

Tetracaine (INN, also known as amethocaine; trade name Pontocaine. Ametop and Dicaine) is a potent local anesthetic of the ester group. It is mainly used topically in ophthalmology and as an antipruritic, and it has been used in spinal anesthesia.

In biomedical research, tetracaine is used to alter the function of calcium release channels (ryanodine receptors) that control the release of calcium from intracellular stores. Tetracaine is an allosteric blocker of channel function. At low concentrations, tetracaine causes an initial inhibition of spontaneous calcium release events, while at high concentrations, tetracaine blocks release completely.

Tetracaine is the T in Tac, a mixture of 5 to 12 per cent tetracaine, 5‱ (per myriad), a half per mille (0.5‰), or .05 per cent (1 part in 2000) adrenaline, and 4 or 10 per cent cocaine hydrochloride used in ear, nose & throat surgery and in the emergemcy department where numbing of the surface is needed rapidly, especially when children have been injured in the eye, ear, or other sensitive locations.

 

Tetracaine Base Application:

It is mainly used topically in ophthalmology and as an antipruritic, and it has been used in spinal anesthesia. Tetracaine is the T in Tac, a mixture of 5 to 12 per cent tetracaine, 5M(per myriad), a half per mille (0.5‰), or .05 per cent (1 part in 2000) , and 4 or 10 per cent hydrochloride used in ear, nose & throat surgery and in the emergemcy department where numbing of the surface is needed rapidly, especially when children have been injured in the eye, ear, or other sensitive locations.

In biomedical research, tetracaine is used to alter the function of calcium release channels (ryanodine receptors) that control the release of calcium from intracellular stores.

Tetracaine is an allosteric blocker of channel function. At low concentrations, tetracaine causes an initial inhibition of spontaneous calcium release events, while at high concentrations, tetracaine blocks release completely.

 

Tetracaine Base Use:

In biomedical research, tetracaine is used to alter the function of calcium release channels (ryanodine receptors) that control the release of calcium from intracellular stores. Tetracaine is an allosteric blocker of channel function. At low concentrations, tetracaine causes an initial inhibition of spontaneous calcium release events, while at high concentrations, tetracaine blocks release completely.

 Tetracaine is the T in Tac, a mixture of 5 to 12 per cent tetracaine, 5M(per myriad), a half per mille (0.5‰), or .05 per cent (1 part in 2000) , and 4 or 10 per cent hydrochloride used in ear, nose & throat surgery and in the emergemcy department where numbing of the surface is needed rapidly, especially when children have been injured in the eye, ear, or other sensitive locations.

Tetracaine is synthesized from 4-butylaminobenzoic acid. The ethyl ester is formed through an acid-catalyzed esterification reaction. Base-catalyzed transesterification is achieved by boiling the ethyl ester of 4-butylaminobenzoic acid with excess 2-dimethylaminoethanol in the presence of a small amount of sodium ethoxide.

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