99%+ Purity Proparacaine Hydrochloride (Proparacaine HCL) CAS: 5875-06-9

Product Details:


Proparacaine HCL Powder Information
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10g powder


99%+ Purity Proparacaine Hydrochloride (Proparacaine HCL) CAS: 5875-06-9


Product Name: Proparacaine Hydrochloride
Proparacaine Hydrochloride CAS: 5875-06-9
Proparacaine Hydrochloride MF: C16H27ClN2O3
Proparacaine Hydrochloride MW: 330.85
EINECS: 227-541-7
Appearance: White Powder
Assay: 99%
Grade: Pharmaceutical Grade
Standard: USP


Proparacaine Hydrochloride Description:

Proparacaine Hydrochloride Ophthalmic Solution USP, 0.5% is a local anesthetic for ophthalmic instillation. Each mL of sterile, aqueous solution contains: Active: Proparacaine Hydrochloride 5 mg (0.5%). Preservative: Benzalkonium Chloride 0.1 mg (0.01%). Inactives: Glycerin as a stabilizer, Hydrochloric Acid and/or Sodium Hydroxide may be added to adjust pH (3.5 to 6.0), and Water for Injection USP.

Proparacaine hydrochloride is designed chemically as 2-(Diethylamino)ethyl 3-amino-4-propoxybenzoate monohydrochloride.


Proparacaine Hydrochloride Use:

Proparacaine Hydrochloride Ophthalmic Solution is indicated for topical anesthesia in ophthalmic practice. Representative ophthalmic procedures in which the preparation provides good local anesthesia include measurement of intraocular pressure (tonometry), removal of foreign bodies and sutures from the cornea, conjunctival scraping in diagnosis and gonioscopic examination; it is also indicated for use as a topical anesthetic prior to surgical operations such as cataract extraction.

The medicine Proparacaine Hydrochloride (HCl) is a local anesthetic used to prevent pain during eye exams or eye surgery. It is commonly sold under the brand name Alcaine in the form of liquid eye drops. It may also be used to alleviate pain after laser eye surgery and other treatments to the eyes. This topical ophthalmic anesthetic is also used for short term relief from corneal burns and corneal abrasions.


Proparacaine Hydrochloride Dosage:

Anesthesia for procedures on eye: deep anesthesia, 1 drop 0.5% ophthalmic solution in each eye every 5 to 10 min for 5 to 7 doses
Anesthesia for procedures on eye: superficial anesthesia, 1 to 2 drops 0.5% ophthalmic solution in each eye before surgery or diagnostic procedure
Tonometry AND/OR tonography procedure: 1 to 2 drops 0.5% ophthalmic solution in each eye before procedure.


Proparacaine Hydrochloride Adverse Reactions:

Occasional short tingling, burning, tears, but less minor. Long-term or repeated application, may have conjunctival hyperemia and acute keratitis.
1. Mental nervous system
There are cases of epileptic seizures after eye drops.
2. Eyes
After a few hours of medication can occur local irritation symptoms, but generally no irritation, burning sensation, conjunctival redness, tear or blink of an eye to increase the number of reactions. Rarely cause hypersensitivity corneal reaction, dilated pupils or ciliary muscle paralysis. Have reported cases of keratitis. Long-term use can cause permanent corneal opacity and visual loss.
3. skin
There are reports of atypical contact dermatitis and delayed hypersensitivity after exposure to this medicine.


Proparacaine Hydrochloride Precautions:

1. contraindications
Allergy to the drug.
2. Caution
(1) patients with hyperthyroidism.
(2) heart disease patients.
3. The effect of drugs on pregnancy
US Department of Medicines and Food (FDA) on the drug's pregnancy safety grading for the C level.
4. The effect of drugs on breastfeeding
It is not clear whether the drug is secreted by milk.

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