99%+ Purity Mepivacaine Hydrochloride (Mepivacaine HCL) Powder CAS: 1722-62-9

Product Details:


Mepivacaine Hydrochloride Powder Information
Mepivacaine Hydrochloride Price1kgAccording to your needs
25kgAccording to your needs
100kgAccording to your needs
Packaging1kg/foil bag,25kg/drum
Delivery timeAbout 7 days
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10g powder


99%+ Purity Mepivacaine Hydrochloride (Mepivacaine HCL) Powder CAS: 1722-62-9


Product Name:Mepivacaine Hydrochloride
Synonym:Mepivacaine HCL; n-(2,6-dimethylphenyl)-1-methyl-2-piperidinecarboxamide hydrochloride; (1-methyl-dl-piperidine-2-carboxylicacid)-2,6-dimethylanilidehydrochloride; 1-methyl-2',6'-pipecoloxylididehydrochloride; 6'-pipecoloxylidide,1-methyl-2monohydrochloride; carbocainehydrochloride; dl-1-methyl-2',6'-pipecoloxylididehydrochloride; dl-mepivacainehydrochloride; n-(2,6-dimethylphenyl)-1-methyl-2-piperidinecarboxamidmonohydrochloride; 1-methyl-2',6'-pipecoloxylidine hydrochloride; N-(2,6-dimethylphenyl)-1-methylpiperidine-2-carboxamide hydrochloride (1:1)
CAS NO.:1722-62-9
Model NO.:1722-62-9
Pure Content:99%
Appearance:White Crystalline Powder


Mepivacaine Hydrochloride Specifications:


AppearanceWhite crystalline solid
SolubilitySoluble in water and methanol, very slightly soluble in chloroform, practically insoluble in ether
PHAbout 4.5
IdentificationA: By IR, To match with working standard 
B: Melting point 149-153°
C: A solution responds to the test for Chloride
Loss on drying≤1.0%
Residual on ignition≤0.1%
Residue solventsShould be matched with the standard 
Chromatographic purity≤ 0.4%
Assay98.0%-102.0%(on the dried basis


Mepivacaine Hydrochloride Description:

Mepivacaine Hydrochloride, a tertiary amine used as a local anesthetic.
It is a white, crystalline, odorless powder soluble in water, but very resistant to both acid and alkaline hydrolysis.It is a white or buff-colored crystalline solid, freely soluble in aqueous solutions of mineral acids, but practically insoluble in water.

Mepivacaine stabilizes the neuronal membrane and prevents the initiation and transmission of nerve impulses, thereby effecting local anesthesia.

Mepivacaine is rapidly metabolized, with only a small percentage of the anesthetic (5 to 10 percent) being excreted unchanged in the urine. Mepivacaine because of its amide structure, is not detoxified by the circulating plasma esterases. The liver is the principal site of metabolism, with over 50 percent of the administered dose being excreted into the bile as metabolites. Most of the metabolized Mepivacaine is probably resorbed in the intestine and then excreted into the urine since only a small percentage is found in the feces. The principal route of excretion is via the kidney. Most of the anesthetic and its metabolites are eliminated within 30 hours. It has been shown that hydroxylation and N-demethylation, which are detoxification reactions, play important roles in the metabolism of the anesthetic. Three metabolites of Mepivacaine have been identified from adult humans: two phenols, which are excreted almost exclusively as their glucuronide conjugates, and the N-demethylated compound (2', 6' - pipecoloxylidide).

The onset of action is rapid (30 to 120 seconds in the upper jaw; 1 to 4 minutes in the lower jaw) and Mepivacaine HCl 3% will ordinarily provide operating anesthesia of 20 minutes in the upper jaw and 40 minutes in the lower jaw.

Mepivacaine HCl 2% with Levonordefrin 1:20,000 provides anesthesia of longer duration for more prolonged procedures, 1 hour to 2.5 hours in the upper jaw and 2.5 hours to 5.5 hours in the lower jaw.

Mepivacaine does not ordinarily produce irritation or tissue damage.
Levonordefrin is a sympathomimetic amine used as a vasoconstrictor in local anesthetic solutions. It has pharmacologic activity similar to that of Epinephrine but it is more stable than Epinephrine. In equal concentrations, Levonordefrin is less potent than Epinephrine in raising blood pressure, and as a vasoconstrictor.


Mepivacaine Hydrochloride Application:

Mepivacaine is indicated for production of local anesthesia for dental procedures by infiltration or nerve block in adults and pediatric patients.

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