99%+ Purity Bupivacaine Hydrochloride (Bupivacaine HCL) CAS :14252-80-3
Product Details:
Bupivacaine HCL Powder Information | ||
Bupivacaine HCL Price | 1kg | According to your needs |
25kg | According to your needs | |
100kg | According to your needs | |
Packaging | 1kg/foil abg,25kg/drum | |
Delivery time | About 7 days | |
Shipping | EMS, Hongkong Post, DHL, TNT, Fedex and so on. | |
Payment terms | WU, MG, Bitcoin, T/T | |
Minimum order | 10g powder |
99%+ Purity Bupivacaine Hydrochloride (Bupivacaine HCL) CAS :14252-80-3
Product name: Bupivacaine Hydrochloride
Synonyms: ;Sensorcaine;Bupivocoine HCl;;marcainehydrochloride;Bupivacaine HCL (USP);P;ah-2250;1-butyl-2’,6’-pipecoloxylididehydrochloride(+-)
Molecular formula: C18H28N2O • HCl • H2O
Molecular Weight: 342.89
EINECS: 241-917-8
CAS: 14252-80-3
Appearance: white or almost white crystalline powder
Heavy Metal: ≤0.001%
The remaining solution: ≤2.0%
Loss on dry 0.1% max
Content: 98.5% -101.5%
Function: As a local anesthesia for surgery and pain killers.
Packing: 1kg/foil bag or 25kg/drum
Standard USP 30
Storage : Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Usage : Bupivacaine is related chemically and pharmacologically to the aminoacyl local anesthetics. It is a homologue of mepivacaine and is chemically related to lidocaine. All three of these anesthetics contain an amide linkage between the aromatic nucleus and the amino. They differ in this respect from the procaine-type local anesthetics, which have an ester linkage.
Bupivacaine Hydrochloride Specifications:
COA
Appearance | White Crystanlline Powder | White Crystanlline Powder | |
Assay | 97.5%-101.0%(*) | 99.86% | |
PH | 4.5-5.5 | 4.64 | |
Sulohated Ash | ≤0.1% | 0.05% | |
Water | 5.0%-7.0% | 6.43% | |
Heavy Metals | ≤5ppm | <5ppm | |
Residual solvements | Methanol ≤0.5% Toluene ≤0.089% | Methanol:0.068% Toluene:0.002% | |
Related Substances | Impurities A≤0.01% | Impurities A: Not detected | |
Unknown Impurities ≤0.1% | Unknown Impurities :0.01% | ||
Total impurities ≤0.5% | Total impurities:0.13% | ||
Conclusion | Conform to the standards of EP8.0 |
Bupivacaine Hydrochloride Description:
Bupivacaine, marketed under the brand name Marcaine among others, is a medication used to decrease feeling in a specific area. It is used by injecting it into the area, around a nerve that supplies the area, or into the spinal canal's epidural space. It is available mixed with a small amount of epinephrine to make it last longer.It typically begins working within 15 minutes and lasts for 2 to 8 hours.
Bupivacaine is contraindicated in patients with known hypersensitivity reactions to bupivacaine or amino-amide anesthetics. It is also contraindicated in obstetrical paracervical blocks and intravenous regional anaesthesia (Bier block) because of potential risk of tourniquet failure and systemic absorption of the drug and subsequent cardiac arrest. The 0.75% formulation is contraindicated in epidural anesthesia during labor because of the association with refractory cardiac arrest. Bupivacaine is related chemically and pharmacologically to the aminoacyl local anesthetics. It is a homologue of mepivacaine and is chemically related to lidocaine. All three of these anesthetics contain an amide linkage between the aromatic nucleus and the amino. They differ in this respect from the procaine-type local anesthetics, which have an ester linkage.
Bupivacaine Hydrochloride Application:
Bupivacaine is indicated for local infiltration, peripheral nerve block, sympathetic nerve block, and epidural and caudal blocks. It is sometimes used in combination with epinephrine to prevent systemic absorption and extend the duration of action. The 0.75% (most concentrated) formulation is used in retrobulbar block.
Bupivacaine Hydrochloride Use:
Bupivacaine hydrochloride injection, USP is available in sterile isotonic solution for injection via local infiltration, peripheral nerve block, and caudal and lumbar epidural blocks. Solution of Bupivacaine hydrochloride injection, USP may be autoclaved. Solution is clear and colorless.
Bupivacaine is related chemically and pharmacologically to the aminoacyl local anesthetics. It is a homologue of mepivacaine and is chemically related to lidocaine. All three of these anesthetics contain an amide linkage between the aromatic nucleus and the amino. They differ in this respect from the procaine-type local anesthetics, which have an ester linkage.
Bupivacaine hydrochloride injection, USP - Sterile isotonic solution containing sodium chloride. The pH of the solution is adjusted to between 4 and 6.5 with sodium hydroxide or hydrochloric acid.
Bupivacaine is an anesthetic (numbing medicine) that blocks the nerve impulses that send pain signals to your brain.
Bupivacaine is used as a local (in only one area) anesthetic.
Bupivacaine is given as an epidural injection into the spinal column to produce numbness during labor, surgery,or certain medical procedures.
Bupivacaine is also used as an anesthetic for dental procedures.
Bupivacaine may also be used for purposes not listed in this medication guide.
Packaging & Delivery Process.