99%+ Purity Aarticaine Hydrochloride (Aarticaine HCL) CAS 23964-57-0
Product Details:
| Aarticaine Hydrochloride Powder Information | ||
| Aarticaine Hydrochloride Price | 1kg | According to your needs |
| 25kg | According to your needs | |
| 100kg | According to your needs | |
| Packaging | 1kg/foil bag,25kg/drum | |
| Delivery time | About 7 days | |
| Shipping | EMS, Hongkong Post, DHL, TNT, Fedex and so on. | |
| Payment terms | WU, MG, Bitcoin, T/T | |
| Minimum order | 10g powder | |
99%+ Purity Aarticaine Hydrochloride (Aarticaine HCL) CAS 23964-57-0
Product Name:Aarticaine Hydrochloride
Synonym: Aarticaine Hydrochloride;Articaine HCl; Articaine hydrochloride; Carticaine hydrochloride; HOE 045; HOE 40045; Methyl 4-methyl-3-(2-(propylamino)propionamido)-2-thiophenecarboxylate, monohydrochloride; Septanest; Septocaine; UNII-QS9014Q792; Ultracain; Ultracaine;
Assay:99%
CAS: 23964-57-0
MW : 320.839
MF: C18H29ClN2O
EINECS:245-957-7
Grade Standard:USP/BP
Export Markets:Global
Trademark:Aarticaine Hydrochloride
Packing:Different Kinds of Special Packing Methods.
Standard:USP/BP
Origin:China
HS Code:29379000
Production Capacity:800 kg /Month
Local Anesthetic Drug 99% Pain Skiller 23964-57-0 Articaine HCl Aarticaine Hydrochloride Power
Appearance: White crystalline powder
Aarticaine Hydrochloride Specifications:
COA
Items | Specifications | Results |
Description | White or almost white powder | Conforms |
Identification | IR& HPLC | Conforms |
Specific Rotation | +32°~+36° | +33.26° |
Related substances | Impurity D , G≤0.3% | Conforms |
Impurity A , B , C , E , F , H , I≤0.2% | Conforms | |
Impurity with RRT 1.23≤0.2% | Conforms | |
Any other impurity≤0.1% | Conforms | |
Total impurity≤1.2% | 0.75% | |
Acetone | ≤1.0% | Conforms |
Water | ≤0.2% | 0.12% |
Assay (by HPLC) | 97.0 ~ 102% | 99.05% |
Particle size | 90%≤10μm | Conforms |
Conclusion | The results conform to EP6 | |
Aarticaine Hydrochloride Description:
Articaine hydrochloride , its CAS NO. is 23964-57-0, the synonyms are 2-Thiophenecarboxylic acid,4-methyl-3-((1-oxo-2-(propylamino)propyl)amino)-, methyl ester, monohydrochloride ; 4-Methyl-3-(2-(propylamino)propionamido)-2-thiophenecarboxylic acid methyl ester HCl ; Articaine HCl ; Methyl 4-methyl-3-(2-(propylamino)propionamido)-2-thiophenecarboxylate, monohydrochloride ; Septanest ; Septocaine.
Articaine is a dental local anesthetic. It is the most widely used local anesthetic in a number of European countries and is available in many countries around the world.
Structure and Metabolism:
The amide structure of articaine is similar to that of other local anesthetics, but its molecular structure differs through the presence of a thiophene ring instead of a benzene ring. Articaine is exceptional because it contains an additional ester group that is metabolized by esterases in blood and tissue. The elimination of articaine is exponential with a half-life of 20 minutes. Since articaine is hydrolized very quickly in the blood, the risk of systemic intoxication seems to be lower than with other anesthetics, especially if repeated injection is performed.
Aarticaine Hydrochloride Application:
Articaine hydrochloride is a local anaesthetic that has been approved overseas for several years. Like other amide anaesthetics, articaine blocks nerve conduction when it is infiltrated around a nerve. This action is prolonged by combining the drug with a vasoconstrictor such as adrenaline.
The combination of articaine and adrenaline can be used for local or regional anaesthesia for dental procedures. Anaesthesia begins within six minutes and lasts for an hour. The half-life of articaine is approximately 1.8 hours. It is metabolised and then mainly excreted in the urine.
Aarticaine Hydrochloride Clinical Use:
(1) Articaine is used for pain control. Like other local anesthetic drugs, articaine causes a transient and completely reversible state of anesthesia (loss of sensation) during (dental) procedures.
(2) In dentistry, articaine is used both for infiltration and block injections, with the block technique yielding the greatest duration of anesthesia.
(3) In people with hypokalemic sensory overstimulation, lidocaine is not very effective, but articaine works well.
