99%+ Purity Oral Pill & Tablet Isotretinoin Raw Powder

Product Details:

 

Isotretinoin Powder Information
Isotretinoin Price100gAccording to your needs
500gAccording to your needs
1000gAccording to your needs
Steroid packagingSpecial stealth packaging through Customs
Delivery timeAbout 7 days
ShippingEMS, Hongkong Post, DHL, TNT, Fedex
Payment termsWU, MG, Bitcoin, T/T
Minimum order10g
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99%+ Purity Oral Pill & Tablet Isotretinoin Raw Powder

 

Isotretinoin Details:

Isotretinoin

Synonym: 13-cis-ra;13-cis-retinoicaci;13-ra;Isoretinoin;isotrex;neovitaminaacid;ro-4-3780
CAS: 4759-48-2
MF: C20H28O2
MW: 300.44
EINECS: 225-296-0
Assay: 99%
Appearance: Orange Crystal Powder
Specification: CP
Chemical Property: The melting point of 174 ~ 175 Centigrade. UV maximum absorption: 354nm ( 39800). Acute toxicity of LD50 (20 days) mice, rats by intraperitoneal injection of:904901 (mg/kg); 3389 > 4000 oral.

 

Isotretinoin Specifications:

COA


Items

Specification

Results

Description

Orange-red crystal

complies

Identification A B

The IR absorption spectrum should correspond

complies
 
Should exhibits maximum absorption at 354nm

complies

Assay

98.0%-102.0%

100.2%

Loss on drying

≤0.5%

0.07%

Tretinoin

≤1.0%

0.1%

Residue on ignition

≤0.1%

0.02%

Heavy metals

<0.002%

<0.002%

Conclusion

The product complies with USP34

 

Isotretinoin Descriptions:

Isotretinoin,also known as 13-cis retinoic acid is an oral pharmaceutical drug primarily used to treat cystic acne. Rarely, it is also used to prevent certain skin cancers (squamous-cell carcinoma), and in the treatment of other cancers. It is used to treat harlequin-type ichthyosis, a usually lethal skin disease, and lamellar ichthyosis. It is a retinoid, meaning it is related to vitamin A, and is found in small quantities naturally in the body. Its isomer, tretinoin, is also an acne drug.

Isotretinoin is primarily used as a treatment for severe acne. The most common adverse effects are a transient worsening of acne (lasting 2-3 weeks), dry lips (cheilitis), dry and fragile skin, and an increased susceptibility to sunburn. Uncommon and rare side effects include: muscle aches and pains (myalgias), and headaches. Isotretinoin is known to cause birth defects due to in utero exposure because of the molecule's close resemblance to retinoic acid, a natural vitamin A derivative which controls normal embryonic development.

In the United States a special procedure is required to obtain the pharmaceutical. In most other countries a consent form is required which explains these risks. Women taking isotretinoin must not get pregnant during, and for 1 month after isotretinoin therapy. Sexual abstinence, or effective contraception is mandatory during this period. Barrier methods by themselves (such as condoms) are not considered adequate due to the unacceptable failure rates of approximately 3%. Women who fall pregnant whilst on isotretinoin therapy are generally counselled to have a termination. Isotretinoin has no effect on male reproduction.

Isotretinoin is used primarily for severe cystic acne and acne that has not responded to other treatments.Acne treatment usually begins with topical retinoids ,in combination with topical antibiotics or antiseptics , followed by oral antibiotics .In women a cyproterone acetate-containing contraceptive pill can be useful if there are no contraindications.

In cases of hormonal acne, such as in women in their 20s and 30s with cyclical acne, often a course of isotretinoin can permanently improve acne obviating the need for lifelong hormonal manipulation.

 

Isotretinoin Functions:

Isotretinoin's main indication is for the treatment of severe cystic acne vulgaris. Many dermatologists also support its use for treatment of lesser degrees of acne that prove resistant to other treatments, or that produce physical or psychological scarring.

It is also somewhat effective for hidradenitis suppurativa and some cases of severe acne rosacea. It can also be used to help treat harlequin ichthyosis, lamellar ichthyosis and is used in xeroderma pigmentosum cases to relieve keratoses. Isotretinoin has been used to treat the extremely rare condition fibrodysplasia ossificans progressiva. It is also used for treatment of neuroblastoma, a form of nerve cancer.

Isotretinoin therapy has furthermore proven effective against genital warts in experimental use, but is rarely used due to potentially severe side effects. In a small-scale study, low dose oral isotretinoin showed considerable efficacy;

Isotretinoin may represent an efficacious and safe alternative systemic form of therapy for RCA of the cervix. Not many studies have been conducted to further confirm its effectiveness. In most countries this therapy is currently unapproved and only used if other therapies failed.

 

Isotretinoin Applications:

Isotretinoin is used to treat severe cystic acne (also known as nodular acne) that has not responded to other treatment (e.g., benzoyl peroxide or clindamycin applied to the skin or tetracycline or minocycline taken by mouth).

Isotretinoin is primarily used as a treatment for severe acne. The most common adverse effects are a transient worsening of acne (lasting 2-3 weeks), dry lips (cheilitis), dry and fragile skin, and an increased susceptibility to sunburn.

As the retinoid, there are strong and fast proliferation inhibition and differentiation of skin gland cell function, effective on severe nodular cystic acne. The gastrointestinal absorption is better, while the local medication invalid. Other drugs used to treat invalid serious acne, cystic acne, acne conglobata, rosacea, ichthyosis, keratosis follicularis and pityriasis rubra pilaris and other skin diseases also have a certain effect.

For severe acne. Anti skin dyskeratosis medicine. For the treatment of severe acne and other disorders

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