Lorcaserin HCl Hemihydrate Approved By FDA
Product Summary:
| Lorcaserin hydrochloride hemihydrate is a white to off-white powder with solubility in water greater than 400 mg/mL. Each Lorcaserin tablet contains 10.4 mg of crystalline lorcaserin hydrochloride hemihydrate, equivalent to 10.0 mg anhydrous lorcaserin hydrochloride, and the following inactive ingredients: silicified microcrystalline cellulose; hydroxypropyl cellulose NF; croscarmellose sodium NF; colloidal silicon dioxide NF, polyvinyl alcohol USP, polyethylene glycol NF, titanium dioxide USP, talc USP, FD&C Blue #2 aluminum lake, and magnesium stearate NF. |
Lorcaserin HCl Hemihydrate Approved By FDA
Product Name:Lorcaserin HCl Hemihydrate
Synonyms: (1R)-8-Chloro-2,3,4,5-tetrahydro-1-methyl-1H-3-benzazepine hydrochloride hemihydrate;Lorcaserin hydrochloride hemihydrate;Lorcaserin HCl 0.5H2O;(R)-8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine dihydrochloride hydrate;(R)-8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine hydrochloride hydrate(2:2:1);R-Lorcaserin hydrochloride hemehydrate;Lorcaserin HCl Hemihydrate;Belviq
CAS: 856681-05-5
MF: 2(C11H14ClN).2(HCl).H2O
Appearance: White powder
Packing: Stealth pack
Minimum order quantity: 10 grams
Assay:99%
Description:
lorcaserin hydrochloride is a serotonin 2C receptor agonist for oral administration used for chronic weight management. Its chemical name is (R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrochloride hemihydrate. The empirical formula is C11H15Cl2N·0.5H2O, and the molecular weight of the hemihydrate form is 241.16 g/mol.
Lorcaserin hydrochloride hemihydrate is a white to off-white powder with solubility in water greater than 400 mg/mL. Each Lorcaserin tablet contains 10.4 mg of crystalline lorcaserin hydrochloride hemihydrate, equivalent to 10.0 mg anhydrous lorcaserin hydrochloride, and the following inactive ingredients: silicified microcrystalline cellulose; hydroxypropyl cellulose NF; croscarmellose sodium NF; colloidal silicon dioxide NF, polyvinyl alcohol USP, polyethylene glycol NF, titanium dioxide USP, talc USP, FD&C Blue #2 aluminum lake, and magnesium stearate NF.
Lorcaserin is indicated as an adjunct to a reduced-calorie diet and increased physical activity for chronic weight management in adult patients with an initial body mass index of:
30 kg/m2 or greater (obese), or 27 kg/m2 or greater (overweight) in the presence of at least one weight related comorbid condition (e.g., hypertension, dyslipidemia, type 2 diabetes)
Dosage:
The recommended dose of Lorcaserin is 10 mg administered orally twice daily. Do not exceed recommended dose
It can be taken with or without food.
Response to therapy should be evaluated by week 12. If a patient has not lost at least 5% of baseline body weight, discontinue Lorcaserin. as it is unlikely that the patient will achieve and sustain clinically meaningful weight loss with continued treatment.
