99% Purity Safe Steroid Solvent Guaiacol (2-Methoxyphenol) CAS 90-05-1
Product Summary:
Guaiacol is a naturally occurring organic compound with the formula C6H4(OH)(OCH3), first isolated by Otto Unverdorben in 1826. Although Guaiacol is biosynthesized by a variety of organisms, this yellowish aromatic oil is usually derived from guaiacum or wood creosote. Samples darken upon exposure to air and light. Guaiacol is present in wood smoke, resulting from the pyrolysis of lignin. The compound contributes to the flavor of many compounds, e.g., roasted coffee. |
99% Purity Safe Steroid Solvent Guaiacol (2-Methoxyphenol) CAS 90-05-1
Guaiacol Details:
Product Name | Guaiacol |
Alias | 90-05-1 |
MF | 2-Methoxyphenol/Guaiacol; GAIACOL; o-Methoxyphenol; o-Hydroxyanisole; 2-Methoxyphenol; Catechol monomethyl ether; Guaiaco; 1-Hydroxy-2-methoxybenzene; a-methoxyphenolsalicyl methyl ether |
MW | C7H8O2 |
CAS | 90-05-1;32-99-4 |
EINECS | 201-964-7 |
Molecular Structure | |
Appearance | Yellowish Aromatic Oil |
Guaiacol Specification:
Items | Standard | Result |
Appearance | Sorrel color liquid | Confirmed |
Guaiacol % | ≥99.5 | 99.52 |
Crystallization(dry) ºC | ≥26.5 | 26.6 |
Moisture % | ≤0.5 | 0.458 |
Substance of low boiling point % | ≤0.2 | 0.18 |
Substance of high boiling point % | ≤0.2 | 0.16 |
Anisole % | ≤0.1 | 0.00 |
Heavy metal (according to Pb) % | ≤0.001 | ≤0.001 |
Arsenic % | ≤0.0003 | ≤0.003 |
Conclusion | The product complies to the enterprise standard |
Guaiacol Description:
Guaiacol is a naturally occurring organic compound with the formula C6H4(OH)(OCH3), first isolated by Otto Unverdorben in 1826. Although Guaiacol is biosynthesized by a variety of organisms, this yellowish aromatic oil is usually derived from guaiacum or wood creosote. Samples darken upon exposure to air and light. Guaiacol is present in wood smoke, resulting from the pyrolysis of lignin. The compound contributes to the flavor of many compounds, e.g., roasted coffee.
Guaiacol Preparation:
In industry, guaiacol is produced by methylation of catechol, e.g., using potash and dimethyl sulfate:
C6H4(OH)2 + (CH3O)2SO2 → C6H4(OH)(OCH3) + HO(CH3O)SO2
Guaiacol Laboratory methods:
Guaiacol can be prepared by diverse routes in the laboratory. 2-Aminoanisole, derived in two steps from anisole, can be hydrolyzed via its diazonium derivative. Guaiacol can be synthesized by the dimethylation of catechol followed by selective mono-demethylation.
C6H4(OCH3)2 + C2H5SNa → C6H4(OCH3)(ONa) + C2H5SCH3
Guaiacol Uses:
Guaiacol is a precursor to various flavorants, such as eugenol and vanillin. Its derivatives are used medicinally as an expectorant, antiseptic, and local anesthetic. It also can be used as an indicator in chemical reactions that produce oxygen. When oxygen binds to it, the complex turns yellowish brown and absorbs light maximally at about 470 nm.
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