L-Arginine
Product Summary:
| L-arginine is one of the 20 amino acids that build up protein. L-arginine is one of the non-essential amino acids, meaning it can be synthesised in the body. L-arginine is a precursor of nitric oxide and other metabolites. It is an important component of collagen, enzymes and hormones, skin and connective tissues. L-arginine plays important roles in the synthesis of various protein molecules; creatine and insulin being the most easily recognised. It may have antioxidant property and reduces accumulation of compounds such as ammonia and plasma lactate, by-products of physical exercise. It also inhibits platelet aggregation and has also been known to decrease blood pressure. When consumed, L-arginine is converted to nitric oxide which aids in the relaxation of blood vessels. The effect is better blood circulation in the body and especially in the extremities; specifically the genitalia. For this reason L-arginine helps in stimulating and maintaining erection. Men with erectile dysfunction benefit especially from the intake of L-arginine rich foods or l-arginine supplement. |
L-Arginine Specification:
COA
Manufacture Standard | AJI97 |
Specific Rotation[α]20D | +26.9°~ +27.9° |
Transmittance | Not less than 98.0% |
Chloride | Not more than 0.020% |
Ammonium | Not more than 0.020% |
Sulfate | Not more than 0.020% |
Iron | Not more than 10ppm |
Heavy Metals | Not more than 10ppm |
Arsenic | Not more than 1ppm |
Other amino acids | conforms |
Loss on drying | Not more than 0.50% |
Residue on ignition | Not more than 0.10% |
Chemical Name | (S)-(+)-Argnine |
Chemical Formula | C6H14N4O2 |
Chemical Weight | 174.20 |
Assay | 99.0%~101.0% |
PH | 10.5~12.0 |
L-Arginine Description:
L-arginine is one of the 20 amino acids that build up protein. L-arginine is one of the non-essential amino acids, meaning it can be synthesised in the body.
L-arginine is a precursor of nitric oxide and other metabolites. It is an important component of collagen, enzymes and hormones, skin and connective tissues. L-arginine plays important roles in the synthesis of various protein molecules; creatine and insulin being the most easily recognised. It may have antioxidant property and reduces accumulation of compounds such as ammonia and plasma lactate, by-products of physical exercise. It also inhibits platelet aggregation and has also been known to decrease blood pressure.
When consumed, L-arginine is converted to nitric oxide which aids in the relaxation of blood vessels. The effect is better blood circulation in the body and especially in the extremities; specifically the genitalia. For this reason L-arginine helps in stimulating and maintaining erection. Men with erectile dysfunction benefit especially from the intake of L-arginine rich foods or l-arginine supplement.
L-Arginine Function:
Arginine is a part of ornithine, which has tremendous effect of physiometry. L-arginine has been used for erectile dysfunction. Like the drug Weilinafil citrate (Viagra), L-arginine is thought to enhance the action of nitric oxide, which relaxes muscles surrounding blood vessels supplying the penis. As a result, blood vessels in the penis dilate, increasing blood flow, which helps maintain an erection. The difference in how they work is that Viagra blocks an enzyme called PDE5 which destroys nitric oxide and L-arginine is used to make nitric oxide.
Heart Health
L-arginine plays a role in many cardiovascular functions, including relaxing the muscles in coronary arteries, lowering blood pressure, reducing symptoms associated with claudication—pain, usually in the extremities due to a lack of blood flow—and helps restore circulation in Raynaud’s phenomenon (fingers become pale, occasionally turn blue in cold temperatures). Additionally, arginine has been shown to reduce blood stickiness in people with high cholesterol and stabilize angina.
When it comes to overall cardiovascular health, a study reported in the April 2012 issue of Annals of Nutrition and Metabolism found that L-arginine and selenium added to a low-calorie diet enriched with legumes regulates cardiovascular risk factors in women with central obesity.
The subjects included 84 premenopausal women with central obesity. Initially, the women consumed an isocaloric diet for two weeks. Next, the researchers assigned the women to one of four groups:
*A low-calorie, control diet enriched with legumes
*5 grams per day of L-arginine plus the control diet
*200 mcg per day of selenium plus the control diet
*L-arginine plus selenium and the control diet
At the beginning of the study and again after three and six weeks, the researchers assessed cardiovascular risk factors including waist circumference, triglycerides, fasting insulin, homeostasis model assessment of insulin resistance index, the inflammatory marker C-reactive protein (CRP) and fasting concentration of nitric oxide.
After six weeks, researchers found that L-arginine significantly reduced waist circumference. L-arginine plus selenium reduced fasting nitric oxide. The low-calorie diet enriched with legumes reduced triglycerides, waist circumference and increased fasting nitric oxide concentrations, as well as reduced CRP during the first half of the study.
The investigators concluded, “These data indicate the beneficial effects of L-arginine on central obesity, selenium on insulin resistance and a hypocaloric diet enriched in legumes on serum concentrations of nitric oxide and triglycerides.”
When it comes to blood pressure specifically, a study published in 2006 found that arginine boosted nitric oxide levels and thereby lowered blood pressure. The researcher gave 29 participants 1,050 mg of L-arginine twice a day for one week. Ten of the participants had borderline to high blood pressure levels, while the other 19 had normal levels.
At the end of the week, 62 percent of participants saw a reduction in systolic blood pressure. In fact, all patients had at least a 4 mmHg decrease. Additionally, diastolic blood pressure was reduced in 69 percent of participants, with an average reduction of 3.7 mmHg.
When the researcher broke down the results by severity of condition, he found that borderline to high participants had an average systolic reduction of 11 mmHg, while the “normal” had a mere 0.22 mmHg reduction. However, on the diastolic side, severity was less of a factor, with borderline to high people enjoying a 4.9 mmHg reduction, while the “normal” participants had a 4.5 mmHg reduction. Vascular elasticity was also improved by an average of 23 percent in all participants.
These findings were supported by a meta-analysis published in 2009, in which researchers reviewed 11 placebo-controlled trials where subjects were supplemented with L-arginine at doses ranging from 4 to 24g/day.The review found that L-arginine significantly lowered systolic and diastolic blood pressure.
Finally, arginine has been shown to protect heart muscle tissue during a bypass surgery,while also improving the health and function of blood vessels.
Sexual Dysfunction
Because arginine helps to increase blood flow in coronary arteries, that means it increases blood flow everywhere. Which is why it has been found to have a Viagra-like activity.
In fact, clinical trials show that arginine can be effective in an impressive 80 percent of cases where circulation problems and reduced NO availability were to blame for sexual dysfunction.
This was seen in a randomized, double-blind, placebo-controlled study published in 1999.8 Researchers tested the effects of high-dose L-arginine in 50 men with erectile dysfunction.
The men were divided into two groups. One received 5 grams of arginine daily for six weeks. The other group received a placebo. At the end of the study period, researchers found that 31 percent of the men taking the arginine enjoyed improved significant improvement in sexual function. Researchers concluded “Oral administration of L-arginine in high doses seems to cause significant subjective improvement in sexual function in men with organic ED.”
