99% + Purity Avanafil (Stendra) Sex Enhancement Powder CAS No.:330784-47-9

Product Details:

 

Avanafil Powder Information
Avanafil Price100gAccording to your needs
500gAccording to your needs
1000gAccording to your needs
Packagingdiscreet packages
Delivery timeAbout 7 days
ShippingEMS, Hongkong Post, DHL, TNT, Fedex and so on.
Payment termsWU, MG, Bitcoin, T/T
Minimum order

10g powder

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99% + Purity Avanafil (Stendra) Sex Enhancement Powder CAS No.:330784-47-9

 

Product Name: Avanafil
Synonym:Stendra,Spedra,PDE5 inhibitor,Sex Enhancement Powders
CAS: 330784-47-9
MF: C23H26ClN7O3
MW: 483.95
MP: 150-152°C
Density: 1.372
Appearance: White to Off-White Cyrstalline Solid

 

Avanafil Specifications:

COA

Test ItemsSpecificationTest Results
DescriptionWhite or almost white crystalline powderWhite crystalline powder
Melting Point191.0~193.0ºC192ºC
Loss of drying≤1.0%0.5%
Heavy Metal≤20ppm15ppm
TLCOnly one spotOnly one spot
Assay≥99.5%

99.91%

 

Avanafil Description:

Avanafil is a PDE5 inhibitor approved for erectile dysfunction by FDA on April 27, 2012 and by EMA on June 21, 2013. Avanafil acts by inhibiting a specific phosphodiesterase type 5 enzyme which is found in various body tissues, but primarily in the corpus cavernosum penis, as well as the retina. Other similar drugs are , tadalafil and vardenafil. The advantage of avanafil is that it has very fast onset of action compared with other PDE5 inhibitors. It is absorbed quickly, reaching a maximum concentration in about 30-45 minutes. About two-thirds of the participants were able to engage in sexual activity within 15 minutes.

 

Avanafil Use:

It is a development of the phosphodiesterase type 5 inhibitors, for the treatment of male sexual dysfunction, at present in the America, EU and Japan have completed phase II clinical trials, phase III clinical trials will start. The product is composed of Japanese Tanabe Pharma Company and VIVUS company development. In addition to oral dosage forms, VIVUS company is also developing Avanafil urethral administration, for not responding to oral dosage forms of patients.

Avanafil is a potent, highly selective phosphodiesterase 5 inhibitor, in vitro experiments showed that the selectivity of phosphodiesterase 5 stronger than . The compound dear compliance weak against other phosphodiesterase, and effect of adenosine receptor decreased, suggesting that the cardiovascular effects of avanafil should be weaker than .

Pre clinical study showed that avanafil and organic nitrate drugs taken in combination to reduce its on blood pressure was significantly weaker than and nitrate drugs with clothes. Moreover, avanafil inhibition of phosphodiesterase 6 is very weak, the relevant visual disturbance suppression may the enzyme phosphodiesterase 5 inhibitor induced and other.

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