99%+ Purity Trimegestone Pure Powder
Product Details:
| Trimegestone Powder Information | ||
| Trimegestone Price | 100g | According to your needs |
| 500g | According to your needs | |
| 1000g | According to your needs | |
| Steroid packaging | Special stealth packaging through Customs | |
| Delivery time | About 7 days | |
| Shipping | EMS, Hongkong Post, DHL, TNT, Fedex | |
| Payment terms | WU, MG, Bitcoin, T/T | |
| Minimum order | 10g powder | |
99%+ Purity Trimegestone Pure Powder
Trimegestone Details:
Product name: Trimegestone
Synonym: Trimegestone [INN]; RU 27987; Estra-4,9-dien-3-one, 17- (2-hydroxy-1-oxopropyl) -17-methyl-, (17beta (S)) -; Totelle Sekvens (17beta) -17 - [(2S) -2-hydroxypropanoyl] -17-methylestra-4 (1) -Li-5-hydroxypropanoyl] -17-methylestra- , 9-dien-3-one
CAS Number: 74513-62-5
Molecular formula: C22H30O3
Molecular weight: 342.4718
InChI: 1 / C22H30O3 / c1-13 (23) 20 (25) 22 (3) 11-9-19-18-6-4-14-12-15 (24) 5-7-16 (14) 17 (18) 8-10-21 (19,22) 2 / h12-13,18-19,23H, 4-11H2,1-3H3 / t13-, 18 +, 19-, 21-, 22 + / m0 / S1
Density: 1.16 g / cm3
Boiling point: 522.6 ° C at 760 mmHg
Flash point: 284 ° C
Steam pressure: 4.16E-13mmHg at 25 ° C
Assay:99%
Appearance:white powder
Trimegestone Descriptions:
Trimegestone (INN) (brand names Ondeva, Totelle Sekvens (both in combination with estrogen)) is a steroidal progestin of the 19-norprogesterone group related to promegestone which is marketed in Europe as a hormonal contraceptive and for use in hormonal replacement therapy for postmenopausal symptoms.
Trimegestone Applications:
Pharmacology
Trimegestone has very high affinity for the progesterone receptor, only weak affinity for the mineralocorticoid receptor, and little or no affinity for other steroid hormone receptors. In accordance, it is described as a very potent and pure progestogen, in fact the most potent progestin of the 19-norprogesterone group (clinically effective in endometriosis at only 0.1 mg/day), and possesses weak antimineralocorticoid activity and no androgenic, antiandrogenic, estrogenic, or glucocorticoid activity.Unlike progesterone, trimegestone does not metabolize into neurosteroids and hence does not influence GABAA receptor signaling or produce sedative side effects.
Pharmacokinetics
The oral bioavailability of trimegestone is 100%.Its elimination half-life is 13.8 hours.It is metabolized mainly via hydroxylation.
