99%+ Purity Ethisterone Pure Powder
Product Details:
| Ethisterone Powder Information | ||
| Ethisterone Price | 100g | According to your needs |
| 500g | According to your needs | |
| 1000g | According to your needs | |
| Steroid packaging | Special stealth packaging through Customs | |
| Delivery time | About 7 days | |
| Shipping | EMS, Hongkong Post, DHL, TNT, Fedex | |
| Payment terms | WU, MG, Bitcoin, T/T | |
| Minimum order | 10g powder | |
99%+ Purity Ethisterone Pure Powder
Ethisterone Details:
Product name: ethisterone
Synonym: Ethisterone, 98%; 17-alpha-ethynyltestosterone; pregneninolone; 17a-ethynyl-17b-hydroxy-4-androsten-3-one; 17a-ethynyl testosterone; anhydrohydroxyprogesterone; ethynyl testosterone; Gestoral
CAS: 434-03-7
EINECS Number: 207-096-5
Formula: C21H28O2
MW: 312.4458
Density: 1.13g / cm3
Melting point: 266-273 ℃
Boiling point: 446.4 ° C at 760 mmHg
Flash Point: 190.2 ° C
Vapor Pressure: 7.59E-10mmHg at 25 ° C
Usage: for the treatment of uterine bleeding or menorrhagia
Assay: 99%
Appearance: White crystalline powder
Ethisterone Specifications
COA
Product name | Ethisterone | |
Appearance | White crystalline powder | |
Water | ≤3% | pass |
Assay | 98 .0~ 102.0% | 99.5% |
Loss on drying | ≤0.5% | 0.2% |
Related substances | total impurities ≤1.0% | Pass |
any individual impurity ≤0.5% | Pass | |
Residual solvents | ethanol ≤0.5% | Pass |
Ethisterone Descriptions:
Ethisterone ( Pranone, Progestoral, Lutocylol, Proluton C, many others), also known as 17α-ethinyltestosterone, pregneninolone, or anhydrohydroxyprogesterone, is a steroidal progestin with androgenic activity which is derived from testosterone and was introduced for medical use in 1939.
Ethisterone was the second progestogen to be marketed (intramuscular progesterone was introduced as Proluton in 1934) and was both the first orally active progestogen and the first progestin (or synthetic progestogen) to be introduced.
Although ethisterone has largely been superseded by newer drugs and is now little used, Ethisterone continues to be available in some countries. Moreover, the 19-nortestosterone progestins, such as norethisterone, are derived from ethisterone and are widely used as hormonal contraceptives and for other indications.
Ethisterone is described as a relatively weak progestogen, similarly to its analogue dimethisterone.
Due to its androgenic activity, ethisterone has been associated with the masculinization of female fetuses in women who have taken it during pregnancy.
Ethisterone Effects：
Androgenic activity
Based on in vitro research, ethisterone and norethisterone are about equipotent in their EC50 values for the androgen receptor (AR), whereas, conversely, norethisterone shows markedly increased potency relative to ethisterone in terms of its EC50 for the progesterone receptor (PR). As such, there is a considerable separation in the ratios of androgenic and progestogenic activity for ethisterone and norethisterone.
Due to its androgenic activity, ethisterone has been associated with the masculinization of female fetuses in women who have taken it during pregnancy.
Estrogenic activity
High dosages of norethisterone and noretynodrel, which are 19-nortestosterone derivatives of ethisterone, were found to be associated with high rates of estrogenic side effects such as breast enlargement in women and gynecomastia in men, as well as with improvement of menopausal symptoms in postmenopausal women.that they are either not estrogenic or are only weak so. As such, ethisterone does not appear to share the estrogenic activity of norethisterone and noretynodrel.
