99%+ Purity Lidocaine Base (Xylocaine) Powder CAS :137-58-6

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Lidocaine Powder Information
Lidocaine Price1kgAccording to your needs
25kgAccording to your needs
100kgAccording to your needs
Packaging1kg/foil bag ,25kg/drum
Delivery timeAbout 7 days
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99%+ Purity Lidocaine Base (Xylocaine) Powder CAS :137-58-6

 

99% Purity Lidocaine Base CAS: 137-58-6
Lidocaine Base
Product Name: Lidocaine Base
Synonyms: 2-(Diethylamino)-N-(2, 6-dimethylphenyl)-acetamide; Lignocaine; 2-diethylaminoacet-2, 6-xylidide; Lidocaine; Xylocaine; N-(2, 6-dimethylphenyl)-N~2~, N~2~-diethylglycinamide; 2-[(2, 6-dimethylphenyl)amino]-N, N-diethyl-2-oxoethanaminium
CAS Registry Number: 137-58-6
Assays: 99%
Packaging: 25kg/drum
Molecular Formula: C14H23N2O
Molecular Weight: 235.3447
EINECS: 205-302-8
Appearance: White Crystalline Powder

 

Lidocaine Base Specifications:

COA



Test Items

Specification

Test Results

Description

White or almost white crystalline powder

White crystalline powder

Melting Point

191.0~193.0ºC

192ºC

Loss of drying

≤1.0%

0.5%

Heavy Metal

≤20ppm

15ppm

TLC

Only one spot

Only one spot

Assay

≥99.5%

99.91%

Conclusion

It complies with the USP 32.

 

Lidocaine Base Description:

1. Lidocaine (INN, BAN) , xylocaine, or lignocaine is a common local anesthetic and class-1b antiarrhythmic drug. Lidocaine is used topically to relieve itching, burning, and pain from skin inflammations, injected as a dental anesthetic, or used as a local anesthetic for minor surgery. It is on the WHO Model List of Essential Medicines, the most important medications needed in a basic healthcare system
2. Topical lidocaine has been shown in some patients to relieve the pain of postherpetic neuralgia (a complication of shingles), though not enough study evidence exists to recommend it as a first-line treatment.[3] Intravenous lidocaine also has uses as a temporary fix for tinnitus. Although not completely curing the disorder, it has been shown to reduce the effects by around two-thirds.
3. Lidocaine is also the most important class-1b antiarrhythmic drug; it is used intravenously for the treatment of ventricular arrhythmias (for acute myocardial infarction, digoxin poisoning, cardioversion, or cardiac catheterization) if amiodarone is not available or contraindicated. Lidocaine should be given for this indication after defibrillation, CPR, and vasopressors have been initiated. A routine prophylactic administration is no longer recommended for acute cardiac infarction; the overall benefit of this measure is not convincing.

 

Lidocaine Base Application:

The efficacy profile of lidocaine as a local anesthetic is characterized by a rapid onset of action and intermediate duration of efficacy. Therefore, lidocaine is suitable for infiltration, block, and surface anesthesia. Longer-acting substances such asbupivacaine are sometimes given preference for subdural and epidural anesthesias; lidocaine, though, has the advantage of a rapid onset of action. Epinephrine (adrenaline) vasoconstricts arteries, reducing bleeding and also delays the resorption of lidocaine, almost doubling the duration of anaesthesia. For surface anesthesia, several available formulations can be used e.g. for endoscopies, before intubations, etc. Buffering the pH of lidocaine makes local freezing less painful.Lidocaine drops can be used on the eyes for short ophthalmic procedures.

Topical lidocaine has been shown in some patients to relieve the pain of postherpetic neuralgia (a complication of shingles), though not enough study evidence exists to recommend it as a first-line treatment.ntravenous lidocaine also has uses as a temporary fix for tinnitus. Although not completely curing the disorder, it has been shown to reduce the effects by around two-thirds.
Lidocaine is also the most important class-1b antiarrhythmic drug; it is used intravenously for the treatment of ventricular arrhythmias (for acute myocardial infarction, digoxin poisoning, cardioversion, or cardiac catheterization) if amiodarone is not available or contraindicated. Lidocaine should be given for this indication after defibrillation, CPR, and vasopressors have been initiated. A routine prophylactic administration is no longer recommended for acute cardiac infarction; the overall benefit of this measure is not convincing.

Inhaled lidocaine can be used as an antitussive (cough suppressor) acting peripherally to reduce the cough reflex. This application can be implemented as a safety and comfort measure for patients who have to be intubated, as it reduces the incidence of coughing and any tracheal damage it might cause when emerging from anesthesia.
Lidocaine, along with ethanol, ammonia, and acetic acid, has also been proven to be effective in treating jellyfish stings, both numbing the affected area and preventing further nematocyst discharge.

 

Lidocaine Base Use:

Lidocaine is used as a pain killer, according to Drugs.com and WebMD. Lidocaine is either injected or delivered intravenously for local and regional pain relief. Lidocaine hydrochloride is also applied topically to reduce the itching associated with eczema, insect bites, minor burns and other injuries to the skin, says WebMD

When lidocaine is applied topically, it is usually applied in a thin layer to the affected area of skin about two to three times a day or as recommended by the patient's physician, says WebMD. Pads impregnated with lidocaine are used once and then discarded. It is used as block anesthesia during childbirth and as a local or infiltration anesthesia during dental procedures, claims Drugs.com.

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