99%+ Purity Carbamazepine (Carbamazepine/ CBZ) Powder CAS No.: 298-46-4
Product Details:
| Carbamazepine Powder Information | ||
| Carbamazepine Price | 1kg | According to your needs |
| 500kg | According to your needs | |
| 1000kg | According to your needs | |
| Packaging | 25kg/drum | |
| Delivery time | About 7 days | |
| Shipping | EMS, Hongkong Post, DHL, TNT, Fedex and so on. | |
| Payment terms | WU, MG, Bitcoin, T/T | |
| Minimum order | 1kg powder | |
99%+ Purity Carbamazepine (Carbamazepine/ CBZ) Powder CAS No.: 298-46-4
Carbamazepine(Tegretol)
Product name:Carbamazepine
Other name:Tegretol
CAS No:298-46-4
Molecular formula:C15H12N2O
Molecular weight:236.27
EINECS:206-062-7
Appearance: White-off crystalline powder
Carbamazepine Specifications:
COA
| Item | Index |
| Appearance | Colorless to pale yellow viscous liquid |
| Content (total alkali) | 29.5%-31.0% |
| Sodium methoxide(NaOCH3) | 28.9-31.0% |
| Sodium hydroxide(NaOH) | ≤0.5% |
| Sodium carbonate(Na2CO3) | ≤0.1% |
| Moisture(H2O) | ≤0.2% |
| Methanol | 69.0-70.7% |
Carbamazepine Description:
(1) Carbamazepine (CBZ), sold under the tradename Tegretol among others, is a medication used primarily in the treatment of epilepsy and neuropathic pain.It is not effective for absence seizures or myoclonic seizures. It is used in schizophrenia along with other medications and as a second line agent in bipolar disorder.Carbamazepine appears to work as well as phenytoin and valproate.
(2) Carbamazepine is an anticonvulsant. It works by decreasing nerve impulses that cause seizures and pain;Carbamazepine is used to treat seizures and nerve pain such as trigeminal neuralgia and diabetic neuropathy.;Carbamazepine is also used to treat bipolar disorder.
Carbamazepine Application:
The mechanism of action of carbamazepine and its derivatives is relatively well understood.[medical citation needed] Carbamazepine is a use-dependant blocker of voltage-gated sodium channels. It is ionised within intracellular fluid, and is then able to bind to activated voltage-gated sodium channels, preventing repetitive and sustained firing of an action potential.This leaves the affected cells less excitable until the drug dissociates. Carbamazepine is also a GABA receptor agonist, as it has also been shown to potentiate GABA receptors made up of alpha1, beta2, and gamma2 subunits.[26] This mechanism may contribute to its efficacy in neuropathic pain and bipolar disorder. Laboratory research has further demonstrated that carbamazepine is a serotonin releasing agent and possibly even a serotonin reuptake inhibitor.
Carbamazepine Side Effects:
Common side effects include nausea and drowsiness. Serious side effects may include skin rashes, decreased bone marrow function, suicidal thoughts, or confusion. It should not be used in those with a history of bone marrow problems. Use during pregnancy may cause harm to the baby; however stopping it in pregnant women with seizures is not recommended. Its use during breastfeeding is not recommended. Care should be taken in those with either kidney or liver problems.
