99%+ Purity Tauroursodeoxycholic Acid (TUDCA) Powder CAS 14605-22-2
Product Details:
| TUDCA Powder Information | ||
| TUDCA Price | 100g | According to your needs |
| 500g | According to your needs | |
| 1000g | According to your needs | |
| Packaging | discreet packages | |
| Delivery time | About 7 days | |
| Shipping | EMS, Hongkong Post, DHL, TNT, Fedex and so on. | |
| Payment terms | WU, MG, Bitcoin, T/T | |
| Minimum order | 5g powder | |
99%+ Purity Tauroursodeoxycholic Acid (TUDCA) Powder CAS 14605-22-2
Product Name: TAUROURSODEOXYCHOLIC ACID
Synonyms: 3ALPHA,7BETA-DIHYDROXY-5BETA-CHOLAN-24-OIC ACID N-(2-SULFOETHYL)AMIDE;TAUROURSODEOXYCHOLIC ACID;TAUROURSODESOXYCHOLIC ACID;2-(((3-alpha,5-beta,7-beta)-3,7-dihydroxy-24-oxocholan-24-ethanesulfonicaci;2-(((3-alpha,5-beta,7-beta)-3,7-dihydroxy-24-oxocholan-24-yl)amino)ethanesul;fonicacid;n-(3-alpha,7-beta-dihydroxy-5-beta-cholan-24-oyl)-taurin;ur906
CAS: 14605-22-2
MF: C26H45NO6S
MW: 499.7
Chemical Properties Off-White Solid
Usage Tauroursodeoxycholate inhibits human cholangiocarcinoma growth via Ca2+-, PKC-, and MAPK-dependent pathways
Tauroursodeoxycholic Acid (TUDCA) Specifications:
COA
| Appearance | White or off-white crystalline powder | White crystalline powder |
| Solubility | Freely soluble in Methanol and ethanol. Sparingly soluble in water. Practically insoluble in ethyl acetate and acetone. | Conforms |
| Specific optical rotation | +45.0° ~ +47.0° | +46.1° |
| Water | 6.0%~8.0% | 7.1% |
| Sulphate Ash | ≤0.1 % | 0.04 % |
| Related substances(TLC) | ||
| Taurine | ≤ 0.2% | Not detected |
| Ursodeoxycholic Acid | ≤ 0.5% | < 0.5% |
| Total unspecified impurities | ≤ 0.5% | Not detected |
| Related substances | ||
| Taurochenodeoxycholic Acid | ≤ 1.0% | 0.02% |
| Any other impurity | ≤ 0.1 % | 0.04% |
| Total unspecified impurities | ≤ 0.5% | 0.05% |
| Heavy metal | ≤ 20 ppm | < 20ppm |
| Residual solvents | ||
| Acetone | ≤ 5000ppm | 2.9 ppm |
| Ethyl acetate | ≤ 5000ppm | Not detected |
| Microbiological Test | ||
| Total plate count | ≤ 1000 CFU/g | <10 CFU/g |
| Yeast and mold | ≤ 100 CFU/g | <10 CFU/g |
Tauroursodeoxycholic Acid (TUDCA) Description:
Tauroursodeoxycholic acid is the more hydrophilic form of ursodeoxycholic acid, which is the more abundant naturally produced bile acid in humans. Tauroursodeoxycholic acid, on the other hand, is produced abundantly in bears and has been used for centuries as a natural remedy in some Asian countries. It is approved in Italy and Turkey for the treatment of cholesterol gallstones and is an investigational drug in China, Unites States, and Italy. Tauroursodeoxycholic acid is being investigated for use in several conditions such as Primary Biliary Cirrhosis (PBC), insulin resistance, amyloidosis, Cystic Fibrosis, Cholestasis, and Amyotrophic Lateral Sclerosis. The only completed clinical trial thus far is a phase III clinical trial comparing tauroursodeoxycholic acid and ursofalk in PBC adult patients, but as of June 2013 no results of this trial have been published.
Tauroursodeoxycholic Acid (TUDCA) Application:
To the steroid user, the incorporation of TUDCA into any cycle regimen is key to help guard your body from bad side-effects. Over time, someone who has been using a moderate amount of oral steroids can put a serious strain on their liver. As the steroids pass through the liver and metabolize, they cause cell
damage. The damage to liver cells by steroids can lead to jaundice and serious liver disease. In addition,steroids can directly inhibit the production and flow of bile from the liver, this is known as cholestasis.
TUDCA has been used to help the bile flow (fix cholestasis) and help cleanse out the liver.TUDCA isn’t just for use during steroid cycles. It should also be used in post cycle therapy (PCT). When you run a steroid cycle, your heart and liver are sure to become strained. Continuing to cleanse your body during post-cycle therapy, when you are off the steroids, can help you release the built up toxins.This should help you feel better and return to your health levels before the cycle started. Those that blast and cruise (BnC) can also take advantage of TUDCA, as it cleanses the liver rather effectively even during BnC runs . In simple terms, it means more blasting and less cruising.
Tauroursodeoxycholic Acid (TUDCA) Benefits:
Studies have shown that TUDCA also helps with blood glucose and insulin.another study showed it aided fat loss and helped neutralize weight in both men and women. So in other words, if you are overweight it will aid in weight loss and if you are underweight it can help you gain some lean mass.
Tauroursodeoxycholic Acid (TUDCA) Indication:
Used in the treatment of cholesterol gallstones. Tauroursodeoxycholic acid is also being investigated for use in several conditions such as Primary Biliary Cirrhosis (PBC), insulin resistance, amyloidosis, Cystic Fibrosis, Cholestasis, and Amyotrophic Lateral Sclerosis.
Tauroursodeoxycholic Acid (TUDCA) Mechanism of Action:
Tauroursodeoxycholic acid is the more hydrophilic form of ursodeoxycholic acid, which is naturally produced in the body. In patients with properly functioning gallbladders, both of these bile acids inhibit liver cholesterol secretion and synthesis as well as intestinal cholesterol absorption allowing for the promotion of cholesterol gallstone dissolution. The mechanism of action of tauroursodeoxycholic acid in the other conditions is still being investigated.
