99% Lisinopril Powder CAS No.:76547-98-3
Product Summary:
| Lisinopril is an inhibitor of ACE (angiotensin-converting enzyme), which removes the C-terminal dipeptide from angiotensin I to form a powerful vasoconstrictor, angiotensin II. ACE is a key regulator of the renin-angiotensin system(RAAS). This compound has an IC50 of 1.2 nM. |
99% Lisinopril Powder CAS No.:76547-98-3
Product Name:Lisinopril
Synonym:N-{N-[(S)-1-Carboxy-3-phenylpropyl]-L-lysyl}-L-proline; N~2~-[(1S)-1-carboxy-3-phenylpropyl]-L-lysyl-L-proline
CAS Number: 76547-98-3
EINECS Number: 278-488-1
Molecular Formula: C21H35N3O7
Molecular Weight: 405.49
InChI：1S/C21H31N3O5/c22-13-5-4-9-16(19(25)24-14-6-10-18(24)21(28)29)23-17(20(26)27)12-11-15-7-2-1-3-8-15/h1-3,7-8,16-18,23H,4-6,9-14,22H2,(H,26,27)(H,28,29)
Boiling Point: 666.4 ° C at 760 mmHg
Flash Point: 356.9 ° C
Vapor Pressure: 1.14E-18mmHg at 25 ° C
Assay: 99%
Grade:Pharm Grade
Standard:USP/EP
Packing: 5KG / tin or according to customer 's requirement
Appearance: white powder
Product Usage:
Used as ntihypertensive medications for angiotensin converting enzyme inhibitors (ACEI)
Lisinopril Specification：
COA
Tests | Specifications | Results |
Appearance | White or off- white crystalline powder | White crystalline powder |
Identification | IR spectrum accordance with that of CRS | Conforms |
Solubility | Soluble in water, sparingly soluble in methanol, practically insoluble in acetone and in anhydrous ethanol | Conforms |
Specific rotation | -43°~-47° | -45.8° |
Water | 8.0%~9.5% | 8.08% |
Sulphated ash | Not more than 0.1% | 0.07% |
Related substances (HPLC) Impurity A Impurity B Impurity C Impurity D Impurity E Impurity F Any unspecified impurity Total impurities |
Not more than 0.3% Not more than 0.3% Not more than 0.3% Not more than 0.3% Not more than 0.3% Not more than 0.3% Not more than 0.10% Not more than 0.5% |
<0.05% No detectable <0.05% No detectable <0.05% 0.07% 0.05% 0.26% |
Assay | 98.5%~101.5%( Calculated on dried basis) | 100.2% |
Residual solvents Acetone Ethanol Dichloromethane Hexane Ethyl acetate |
Not more than 5000ppm Not more than 5000ppm Not more than 600ppm Not more than 890ppm Not more than 5000ppm |
<75ppm No detectable No detectable No detectable No detectable |
Conclusion | Complies with EP 7.0 | |
Lisinopril Description:
Lisinopril is an inhibitor of ACE (angiotensin-converting enzyme), which removes the C-terminal dipeptide from angiotensin I to form a powerful vasoconstrictor, angiotensin II. ACE is a key regulator of the renin-angiotensin system(RAAS). This compound has an IC50 of 1.2 nM.
Packaging & Shipping:
25kg/drum or according to customer's requiement
Transit could be DHL,UPS,TNT,EMS,Fedex,and so on.
For mass orders, it will be delivered by air or sea.
Depending on your location, please allow 1-5 business days for your order to arrive.
For small order, please expect 3-7 days by UPS DHL EMS.
For mass order, please allow 5-8 days by Air, 15-30 days by Sea.
